Fevarin pills 100mg №15

Packaging

15 pieces

Mechanism of action

FEVARIN is an antidepressant. The mechanism of action is associated with selective inhibition of serotonin reuptake by brain neurons and is characterized by minimal effect on noradrenergic transmission. Fevarin has a weak ability to bind to α- and β-adrenergic receptors, histamine, m-cholinergic receptors, dopamine and serotonin receptors.

Indications and usage

- treatment and prevention of depression;

- treatment of symptoms of obsessive-compulsive disorders.

Contraindications

- simultaneous use with tizanidine;

- simultaneous use with MAO inhibitors (the interval between the withdrawal of the MAO inhibitor and the start of treatment with Fevarin should be at least 2 weeks);

- children's age up to 8 years;

- hypersensitivity to fluvoxamine maleate or to other components of the drug.

Dosage and administration

In the treatment of depression, the recommended initial dose is 50 mg or 100 mg 1 time / day, in the evening. Increasing the dose should be carried out gradually. An effective dose, usually 100 mg / day, is selected individually depending on the patient's response to treatment. The daily dose can reach 300 mg.

Doses of more than 150 mg / day should be divided into several doses.

In accordance with official WHO recommendations, antidepressant treatment should be continued for at least 6 months after the treatment of a depressive episode.

To prevent recurrence of depression, it is recommended to administer Fevarin in a dose of 100 mg 1 time / day.

When treating obsessive-compulsive disorders, the recommended starting dose is 50 mg / day for 3–4 days. Increasing the dose should be carried out gradually to achieve an effective daily dose, which is usually 100-300 mg. The maximum effective dose for adults is 300 mg / day. Doses up to 150 mg can be taken 1 time / day, preferably in the evening. Doses of more than 150 mg / day are recommended to be divided into 2 or 3 doses.

For children over 8 years old and adolescents, the initial dose is 25 mg / day for 1 reception. Maintenance dose - 50-200 mg / day. The maximum dose is 200 mg / day. Doses of more than 100 mg / day are recommended to be divided into 2 or 3 doses.

With the development of an adequate therapeutic effect, treatment can be continued with an individually selected daily dose. If improvement is not achieved after 10 weeks of treatment, Fevarin should be canceled. Given that obsessive-compulsive disorders are chronic, it may be considered appropriate to extend the course of treatment with Fevarin for more than 10 weeks in patients with an adequate therapeutic effect. Selection of the minimum effective maintenance dose should be done individually and with caution.Some clinicians recommend concomitant psychotherapy in patients with good pharmacotherapy effects.

In case of hepatic or renal failure, treatment should begin with the lowest dose under strict medical supervision.

Fevarin pills should be taken without chewing and washing down with a small amount of water.

Overdosage

Symptoms: the most characteristic are nausea, vomiting, diarrhea, drowsiness, dizziness. There are reports of cardiac abnormalities (tachycardia, bradycardia, arterial hypotension), abnormal liver function, convulsions, coma.

To date, more than 300 reports have been received of Fevarin’s deliberate overdose. The highest recorded dose was 10 g (the patient was cured as a result of symptomatic therapy). More serious complications were observed in cases of deliberate overdose of Fevarin against the background of concomitant pharmacotherapy.

Treatment: gastric lavage, which should be carried out as soon as possible after taking the drug; conduct symptomatic therapy. In addition, it is recommended to repeatedly receive Activated carbon. There is no specific antidote. Forced diuresis or dialysis is impractical.

The drug should be stored in a dry, protected from direct sunlight, out of reach of children, at a temperature not higher than 25 ° C.