Kestine pills 10mg №10

Mechanism of action

Histamine H blocker₁-receptors. It has antiallergic effect.
The drug does not cause pronounced anticholinergic and sedative effects. No effect of Kestine on the QT ECG interval was noted, even when used at a dose of 80 mg.
After taking the drug inside a pronounced antiallergic effect develops after 1 h and lasts for 48 hours. After a 5-day course of Kestine treatment, antihistamine activity persists for 72 hours due to the action of active metabolites.

Indications and usage

- seasonal and / or year-round allergic rhinitis (caused including household, pollen, epidermal, food, drug allergens);
- urticaria (caused including household, pollen, epidermal, food, insect, drug allergens, exposure to the sun, cold);
- Allergic diseases and conditions caused by an increased release of histamine.

Overdosage

Treatment: there is no specific antidote. Recommended gastric lavage, medical observation; if necessary, conduct symptomatic therapy.

Drug Interactions

No clinically significant drug interaction of Kestine with theophylline, indirect anticoagulants, cimetidine, diazepam, ethanol and ethanol-containing drugs was detected.

Storage conditions

The drug should be stored in a dark place, out of the reach of children, at a temperature of 15 ° to 30 ° C. Shelf life - 3 years.

The drug is approved for use as a means of OTC.