Acridem Gent Cream 30g

Cream

Composition

1 gram of cream contains 0.64 mg betamethasone dipropionate (equivalent to 0.5 mg betamethasone) and Gentamicin sulfate - 1 mg.

Packaging

Tuba 30

Mechanism of action

Akriderm GENTA is a combined preparation for external use, which has anti-inflammatory, anti-allergic and anti-bacterial action.
Betamethasone dipropionate - glucocorticosteroid, has anti-inflammatory, antiallergic, antiexudative, anti-edema and antipruritic action. It inhibits the accumulation of leukocytes, the release of lysosomal enzymes and proinflammatory mediators in the inflammatory focus, inhibits phagocytosis, reduces vascular tissue permeability, prevents the formation of inflammatory edema.
Gentamicin - broad-spectrum antibiotic from the group of aminoglycosides. It has a bactericidal effect against pathogens of primary and secondary bacterial infections of the skin. Active against gram-negative bacteria: Pseudomonas aeruginosa, Aerobacter aerogenes, Escherichia coli, Proteus vulgaris, Klebsiella pneumoniae; Gram-positive bacteria: Streptococcus spp. (sensitive strains of beta and alpha hemolytic streptococcus group A), Staphytococcus spp. (coagulase-positive, coagulase-negative and some strains producing penicillinase). Inactive against anaerobes, fungi and viruses.

Indications and usage

Treatment of steroid-sensitive dermatoses, complicated by primary and / or secondary bacterial infection, eczema (atopic, pediatric, mono-type), limited and diffuse allergic dermatoses, including those complicated by gentamicin-sensitive infection, dermatitis (simple and allergic), atopic dermatitis, sunny dermatitis, exfoliative and radiation dermatitis, diaper rash, psoriasis, pruritus.

Contraindications

Hypersensitivity to the drug. Skin tuberculosis, viral skin infections, vaccinations, perioral dermatitis, rosacea (rosacea).

Pregnancy and Breastfeeding

Perhaps if the expected effect of therapy for the mother outweighs the potential risk to the fetus. Contraindicated in pregnancy in large doses and for a long time. At the time of treatment should stop breastfeeding.

Dosage and administration

The drug Akriderm GENTA is applied with a thin layer on the inflamed surface twice a day, slightly rubbing. In milder cases, single use is sufficient. The duration of treatment is determined individually and depends on the nosological form and severity of the disease and is usually 1-2 (rarely 4 weeks).
If necessary, a long course of therapy is recommended to use the drug less often, for example, every other day.
In the treatment of chronic diseases under the constant supervision of a physician, treatment should continue for some time after the disappearance of all symptoms in order to avoid recurrence of the disease.
The use of the drug in children under 12 years of age is carried out under the supervision of the attending physician.

Adverse reactions

Burning, dry skin, folliculitis, hypertrichosis, hypopigmentation, allergic contact dermatitis, skin atrophy, stretch marks, prickly heat.

Special notes

The drug is not used in ophthalmology. Avoid getting the cream in the eyes, on damaged skin and open wound sites. In order to increase the effectiveness of therapy, it is possible to use occlusive dressings. It must be borne in mind that this increases the transdermal absorption of betamethasone and gentamicin, which leads to an increased risk of systemic side effects. When a persistent bacterial or fungal microflora appears, the use of the drug should be discontinued and appropriate therapy should be prescribed. possible development of cross-resistance with aminoglycoside antibiotics.

Overdosage

Acute overdose is unlikely, however, with excessive or prolonged use of the drug, chronic overdose is possible, accompanied by signs of hypercortisolism: hyperglycemia, glycosuria, reversible inhibition of adrenal cortex function, manifestation of Cushing's syndrome.
Treatment. Corresponding symptomatic treatment is indicated. In the case of chronic toxic effects, a gradual withdrawal of the drug is recommended.

At a temperature of 15 to 25 ° C in the reach of children.