

PHYSIOTENZE
Physiotens has a hypotensive effect.
Arterial hypertension.
Hypersensitivity to Physiotens components;
sick sinus syndrome, marked bradycardia;
age up to 18 years (efficacy and safety have not been established).
With caution:severe chronic renal failure and severe liver failure (due to lack of experience with the application);
hemodialysis.
There are no clinical data on the negative impact on the course of pregnancy. However, care should be taken when prescribing Physiotens to pregnant women. During the period of treatment it is recommended to stop breastfeeding, because Moxonidine passes into breast milk.
From the side of the central nervous system: dizziness, headache, drowsiness, sleep disturbance.
Cardiovascular: excessive decrease in blood pressure, orthostatic hypotension.
On the part of the digestive tract: dry mouth, nausea.
From the skin and subcutaneous adipose tissue: skin rash, itching, angioedema.
General: asthenia.
These symptoms usually decrease gradually during the first weeks of treatment.
Physiotens are taken orally, regardless of the meal, the initial dose (in most cases) - 0.2 mg per day; the maximum daily dose is 0.6 mg (divided into 2 doses); maximum single dose - 0.4 mg;
in case of renal insufficiency (Cl of creatinine 30-60 ml / min) and in patients on hemodialysis, a single dose is 0.2 mg, the maximum daily dose is 0.4 mg.