Buy Uro-bladder protector 50ml
  • Buy Uro-bladder protector 50ml

Uro-bladder protector 50ml

$129.81
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Release form

Injection

Mechanism of action

Hyaluronic acid is a high molecular weight glycosaminoglycan that consists of repetitive disaccharides of N-acetylglucosamine and glucuronic acid. Hyaluronic acid is a component of all body tissues and is the most significant component of the extracellular matrix and thus constitutes a significant proportion of glycosaminoglycans of the urinary bladder urethra, urethra (urethra).

The medical product Uro-Gial is a viscoelastic protector of the intercellular substance of the urinary bladder urothelium. When introduced into the bladder cavity, it creates a viscoelastic film on the mucosal surface that protects it from external influences during various manipulations (urethroscopy, cystoscopy, TUR of the prostate gland and bladder, pelvic radiation therapy, etc.).

Indications

Temporary protection of the mucous membrane of the bladder during various manipulations (urethro-cystoscopy, radiation therapy, etc.). In addition, numerous scientific studies have proven the effectiveness of sodium hyaluronate for the following diseases:

  • Chronic / recurrent cystitis;
  • Radiation cystitis;
  • Interstitial cystitis;
  • Overactive bladder (as part of complex therapy with M-cholinolytics or vanilloid receptor agonists (RTX))

Contraindications

  • Hypersensitivity to one of the components of the composition of Uro-Hyal,
  • Pregnancy,
  • lactation,
  • children.

Special notes

Uro-Hyal preparation is intended only for insertion into the cavity of the bladder with the help of a urological catheter.
Exudate the introduction, strictly following the rules of asepsis.
Before use, check the integrity and tightness of the bottle: do not use the drug if the bottle or its cap is damaged, and also check the integrity of the packaging of the syringe, needle and urological catheter. If they are damaged, the use of the drug is not permissible.
Do not use after the expiration date.
"URO-GIAL" is intended for instillation into the bladder, which must be performed by a physician who has special training in a specially equipped room, in compliance with all aseptic rules.

Composition

1 ml of solution contains: sodium hyaluronate 0.8 mg, sodium dihydrogen phosphate monohydrate 0.45 mg, disodium phosphate anhydrous 2 mg, sodium chloride 8.5 mg ± 0.05, deionized water q.s.

Dosage and administration

1. Receive written informed consent of the patient to the manipulation.
2. Explain to the patient the features of the procedure and intravesical instillation therapy (approximately as indicated below):
a) if the source of pain is the bladder, then you can feel relief after 5 - 15 minutes after the injection of the mixture;
b) in the initial phase of treatment, you may need intravesical instillations more often than once a week.
c) try to keep the injected mixture in your bladder for at least 30 minutes, but not more than 2 hours.
d) sometimes (rarely) side effects occur, which you should immediately notify the doctor.
e) extremely rarely, there is a rebound effect, when after 5-6 hours after drug administration, pain returns with greater intensity.
e) Instillation therapy may require more procedures than planned.
3. Prepare the patient for catheterization on the urogynecological chair.
4. Wash your hands. Wear non-sterile gloves.
5. Treat the external opening of the urethra with an antiseptic.
6. Insert a lubricant anesthetic into the urethra, leaving a small amount of gel to lubricate the catheter.
7. Take off the gloves.
8. Wash your hands.
9.Intake the drug (s) in a 60 ml syringe. (If using a combination of drugs, then pre-mix them in a bottle with "URO-GIAL" using a syringe of 10 ml).
10.Open the catheter packaging.
11. Put on sterile gloves.
12. While maintaining sterility, apply a small amount of anesthetic lubricant on the tip of the catheter and gently insert the catheter into the urethra and then into the bladder.
13. Empty the bladder, then attach the syringe to the catheter and slowly insert the solution into the bladder.
14. Remove the catheter from the urethra.
15. Drop used supplies into special containers.
16. Remove the gloves.
17. Wash your hands.
18. Make an entry in the outpatient card and patient appointments.

  • "URO-GIAL" is introduced intravesically, once a week. The course ranges from 4 to 12 instillations.
  • The bottle should be removed from the refrigerator at least 20 minutes before use. Before use, the temperature of the bottle should be at least 20C.
  • Before the introduction of the drug "URO-GIAL", should empty the bladder.
  • The drug "URO-GIAL" is introduced into the cavity of the bladder using a urological catheter for at least 30 minutes.

Side effects

No adverse events were identified. Individual intolerance may occur.

Drug interaction

Incompatibility between sodium hyaluronate and quaternary ammonium salts, such as benzalkonium chloride, is noted. Uro-Gial should not be allowed to come into contact with such preparations or with medical and surgical instruments treated with such preparations.

Packaging

Bottle of 50 ml.

Storage conditions

Store at a temperature of +2 ° C to +15 ° C.

Pharmacy sales terms

Prescription doctor