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Pharmacodynamics:
The drug has anti-inflammatory and antiaggregatory effects, stimulates the muscles of the bladder.
The active ingredients of the prostate extract belong to the group of peptide bioregulators - cytomedines. These drugs are peptides with a molecular weight of from 1 to 10 kDa. Low molecular weight peptides of a para- or autocrine nature function as trans-specific intracellular and intercellular messengers.
Prostate peptides reduce blood clotting time and increase the antiaggregatory activity of the vascular wall, improve blood microcirculation, increase blood fibrinolytic activity, increase the contractile activity of the detrusor myocytes in vivo, in vitro.
They have immunomodulatory and immunostimulating action, enhance the synthesis of antihistamine and antiserotonin antibodies.
The use of peptide bioregulators in the treatment of chronic prostatitis is based on the ability of these drugs to restore microcirculation, to have an indirect anti-inflammatory effect by increasing the synthesis of antihistamine and antiserotonin antibodies, as well as their immunomodulating and immunostimulating effects.
Treatment of benign prostatic hyperplasia is based on the most important biological effect of cytomedines: organotropic,allowing to regulate the processes of differentiation and cell function in the organ from which they are isolated.
Pharmacokinetics:
As a peptide drug, it is cleaved by cellular proteases to amino acids. Cumulative action has not.
Indications:
Chronic abacterial prostatitis, condition before and after operations on the prostate gland, benign prostatic hyperplasia.
Contraindications:
Individual intolerance (including history of hypersensitivity).
Dosage and administration:
The drug is used rectally after a bowel movement or a cleansing enema. Moistening the suppository with water, inject it deep into the anus.
Apply 1 suppository 2 times a day (morning and evening). After the introduction of the drug, it is desirable to stay in bed for 30-40 minutes.
The duration of treatment is 5-10 days. According to the testimony may be repeated courses; It is recommended to carry out no earlier than 2-4 weeks.
Side effects:
Often - 1-10%; sometimes 0.1–1%; rarely, 0.01–0.1%; very rarely - less than 0.01%, including some cases.
Very rarely - allergic reactions; often - itching in the anus; sometimes - diarrhea, flatulence.
Overdose:
Currently, overdose cases have not been reported.
Interaction:
Negative interaction was not observed.
The drug can be used in complex therapy.
Special instructions:
Treatment of chronic prostatitis should be complex, involving the use of different groups of drugs andnon-drug treatments.
When treatment is recommended to analyze the secret of the prostate gland.
Impact on the ability to drive trans. Wed and fur.:
The drug does not affect the ability to drive vehicles, mechanisms.
Storage conditions:
At a temperature not higher than 25 ° С.
Keep out of the reach of children.
Shelf life:
2 years.
Do not use after the expiration date of the drug indicated on the package.