Carniten solution for internal use 1000mg/10ml №10

Mechanism of action

Anabolic, antihypoxic, regenerating, antithyroid.

It is easily absorbed from the intestines, penetrates into all tissues, the greatest concentrations are created in the skeletal muscles and myocardium. C_max is reached after 3 hours and remains at the therapeutic level for up to 9 hours. Excreted by the kidneys unchanged (more than 80% for 24 hours).

Indications and usage

Congenital primary and secondary Carnitine deficiency; acquired secondary carnitine deficiency with total parenteral nutrition, chronic hemodialysis, valproic acid intake, intense physical exertion; prematurity, lag in growth and body mass, perinatal CNS pathology in newborns and premature infants; angina pectoris, acute myocardial infarction, cardiogenic shock, post-infarction conditions, diseases of the peripheral arteries.

In / in slowly. Secondary deficiency in hemodialysis: 2 g once (after the procedure); acute myocardial infarction: 100–200 mg / kg / day in 4 doses or continuous administration for the first 48 hours, followed by a 2-fold reduction in the dose; cardiogenic shock: in / in before the patient leaves the shock. Inside, a single dose from the vial is diluted with a glass of water.Primary and secondary deficiency in genetic diseases: children under 2 years old - 150 mg / kg / day, 2-6 years old - 100 mg / kg / day, 6-12 years old - 75 mg / kg / day, from 12 years old and adults 2-4 g / kg / day; secondary deficiency in hemodialysis: 2-4 g per day; angina and post-infarction conditions: 2-6 g per day.

Adverse reactions

Gastrointestinal disorders (after oral administration), mild myasthenic symptoms (in patients with uremia).

Contraindications

Hypersensitivity to the drug.

Pregnancy and breastfeeding

With no restrictions.