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Androcur pills 10mg №15
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Mechanism of action
Antiandrogenic, progestin. Active ingredient Androkura weakens the influence of male sex hormones (androgens), which are also produced in the female body. Therefore, in women, ANDROCUR eliminates pathological changes that are caused by enhanced androgen formation or hypersensitivity to them: strong hair growth of the face and other parts of the body, as well as acne and seborrhea, which are largely due to androgen-dependent enhanced function of sebaceous glands.
Indications and usage
Inoperable prostate cancer, metastatic or inoperable prostate cancer (without and after orchiectomy, as well as in combination with gonadotropin-releasing hormone agonists), increased sexual desire with sexual deviations; antiandrogen therapy in inoperable prostate carcinoma.
Manifestations of moderate androgenization in women, such as:
- moderate hirsutism (pathological body hair of the face and body of moderate severity);
- moderate androgenic alopecia (moderate androgeny baldness caused by androgens);
- severe and moderate forms of acne and seborrhea.
Contraindications
- pregnancy and breastfeeding;
- liver diseases (includingDubin-Johnson syndrome, Rotor syndrome, history of liver cancer or present);
- idiopathic jaundice or persistent itching during a previous pregnancy;
- herpes pregnant with a history of;
- cachexia;
- severe chronic depression;
- thromboembolism (including in history);
- severe diabetes mellitus with diabetic angiopathy;
- sickle cell anemia;
- hypersensitivity to any of the components of the drug;
- adolescence (until the end of puberty).
Dosage and administration
The initial dose Androcur - 1 tab. (50 mg 2 times a day). If necessary, the dose can be increased to 200-300 mg / day. The course of treatment is set for patients individually for each treatment with the treatment.
Adverse reactions
Changes in body weight and libido, tension and tenderness of the mammary glands, and depressive states may occur. Rarely - allergic reactions and itching. At the beginning of treatment with Androcur, abdominal pain, nausea, fatigue, dry skin, apathy, depressive states or anxiety, decreased concentration of attention may occur. Rarely, allergic reactions, increase or decrease in body weight may occur. Perhaps the appearance of gynecomastia and the suppression of spermatogenesis, a reversible decrease in sexual desire and potency. Prolonged suppression of the production of androgens in rare cases can lead to osteoporosis. In isolated cases, when using high doses, there is a feeling of lack of air and abnormal liver function.
Special notes
Before starting treatment with Androcur, a general medical and gynecological examination (including breast examination and cervical mucus smear) should be carried out. It is also necessary to exclude pregnancy.
In patients with diabetes, the need for oral hypoglycemic agents or insulin may change. Patients suffering from diabetes during treatment with Androcur must be under the supervision of a physician. During the period of treatment, care should be taken when practicing activities that require increased attention. During treatment, periodic monitoring of liver function is necessary.
Storage conditions
In a dry, dark place at a temperature of 10 - 25 ° C.
Androkur