Maninil pills 1.75 mg №120

Maninil 1.75 /Maninil 1.75

Composition and release form

Maninil 1.75 - tablets: 1 table. contains micronized glibenclamide 1.75 mg; excipients: lactose monohydrate; potato starch; methyl hydroxyethyl cellulose; colloidal silicon dioxide; Magnesium stearate; cochineal red A (dye E124);

in glass bottles of 120; in a cardboard box of 30 or 60 pcs.

pharmachologic effect

Maninil 1.75 has a hypoglycemic effect.

Indications

Type 2 diabetes mellitus (insulin-independent) with the ineffectiveness of diet therapy, loss of body weight with obesity and sufficient physical activity.

Contraindications

Hypersensitivity (including to sulfonamide drugs and other sulfonylurea derivatives), type 1 diabetes mellitus (insulin-dependent), metabolic decompensation (ketoacidosis, precoma, coma), condition after pancreatic resection, severe liver and kidney diseases, some acute conditions (for example, decompensation of carbohydrate metabolism in infectious diseases, burns, injuries or after major surgeries when insulin therapy is indicated), leukopenia, intestinal obstruction, gastric paresis, conditions involving a violation of food intake and the development of hypoglycemia, pregnancy and breastfeeding.

Side effects

Hypoglycemia is possible (when skipping meals, overdosing the drug, with increased physical exertion, as well as with heavy use of alcohol).

On the part of the digestive tract: sometimes - nausea, vomiting; in some cases - cholestatic jaundice, hepatitis.

From the hematopoietic system: extremely rare - thrombocytopenia, granulocytopenia, erythrocytopenia (up to pancytopenia), in some cases - hemolytic anemia.

Allergic reactions: extremely rare - skin rash, fever, joint pain, proteinuria.

Others: at the beginning of treatment, transient accommodation disorder is possible. In rare cases - photosensitivity.

Dosage and administration

Maninil 1.75 is taken orally, in the morning and in the evening, before eating, without chewing. Dose set individually, depending on the severity of the disease.

The initial dose is 1/2 table., The average - 2 table. per day, maximum - 3, in exceptional cases - 4 tab. per day. If necessary, receive higher doses of the drug (up to 14 mg / day) are transferred to Maninil 3.5 mg.

Storage conditions and shelf life

Store in a dark place at a temperature not exceeding 25 ° C. Shelf life - 3 years.