Sumamed powder for suspension 100mg/5ml 23ml

Indications and usage

Infectious and inflammatory diseases caused by microorganisms sensitive to the drug:
- infections of the upper respiratory tract and ear (bacterial pharyngitis, tonsillitis, sinusitis, otitis media);
- infections of the lower respiratory tract (bacterial bronchitis, interstitial and alveolar pneumonia, exacerbation of chronic bronchitis);
- infections of the skin and soft tissues (chronic migrating erythema - the initial stage, Lyme disease, erysipelas, impetigo, secondary dermatosis);
- sexually transmitted infections (urethritis, cervicitis);
- Diseases of the stomach and duodenum associated with Helicobacter pylori.

Contraindications

- severe violations of the liver and kidneys;
- Hypersensitivity to macrolide antibiotics;
with caution: during pregnancy and lactation, in disorders of the liver and kidneys, patients with impaired or susceptible to arrhythmias and lengthening of the QT interval.

Pregnancy and Breastfeeding

In pregnancy, the drug should be administered only if the expected benefit to the mother outweighs the potential risk to the fetus. If it is necessary to introduce Sumamed women during lactation, it is necessary to decide on the termination of breastfeeding.

Dosage and administration

The drug is administered orally 1 time per day, at least 1 hour before or 2 hours after a meal.

The required dose is measured using a syringe or measuring spoon: with a body weight of up to 15 kg, a syringe is used, with a body weight above 15 kg a measuring spoon.

With infections of the upper and lower respiratory tract, ENT organs, skin and soft tissues (except for chronic migrating erythema) prescribed at the rate of 10 mg / kg body weight 1 time / day for 3 days, course dose - 30 mg / kg.

In chronic erythema migrans: 
in 1 day at a dose of 20 mg / kg of body weight and then from 2 to 5 days - daily at a dose of 10 mg / kg of body weight, a course dose of 60 mg / kg.

11 ml of water are added to the contents of the vial and shaken. The volume of the resulting suspension is 25 ml. The shelf life of the prepared suspension is 5 days.

Before taking the contents of the vial thoroughly shaken to obtain a homogeneous suspension. Immediately after taking the suspension, the child is allowed to drink a few sips of water in order to wash off and swallow the remaining amount of suspension in the oral cavity.

After use, the dosing syringe is disassembled, washed with running water, dried and stored in a dry place.

Adverse reactions

Rarely (in 1% of cases and less).
Gastrointestinal: melena, cholestatic jaundice, nausea, vomiting, diarrhea, constipation, loss of appetite, gastritis, reversible moderate increase in liver enzymes.
Urogenital: nephritis.
From the reproductive system: vaginal candidiasis.
Cardiovascular: palpitations, chest pain.
Nervous system: dizziness, headache, vertigo, drowsiness, fatigue; in children - headache (in the treatment of otitis media), hyperkinesia, anxiety, neurosis, sleep disorders.
Allergic reactions: skin rash, angioedema, urticaria, conjunctivitis.
Dermatologic: photosensitivity, itching.
From the laboratory indicators: in some cases - neutrophilia, eosinophilia (altered parameters return to normal after 2-3 weeks after discontinuation of treatment).

Special notes

In case of skipping a single dose of the drug - the missed dose should be taken as early as possible, and the next - with intervals of 24 hours.
The patient should be warned about the need to inform the doctor about the occurrence of any side effect.

Antacids (containing aluminum, magnesium), ethanol and food intake greatly reduce the absorption of Azithromycin (capsules and suspension), so the drug should be taken at least 1 hour before or 2 hours after taking these drugs and food.
Azithromycin, unlike other macrolide antibiotics, is not associated with cytochrome P isoenzymes.₄₅₀. To date, no interactions with theophylline, terfenadine, Carbamazepine, triazolam, Digoxin have been observed.
Macrolides when taken simultaneously with cycloserine, indirect anticoagulants, methylprednisolone,felodipine and drugs that undergo microsomal oxidation (cyclosporine, hexobarbital, ergot alkaloids, valproic acid, disopyramide, Bromocriptine, phenytoin, oral hypoglycemic agents), slow down the excretion, increase the concentration and toxicity of these drugs, while using the dosage and dosage of these drugs, used with the use of the dosage, and using the dosage, increased the concentration and toxicity of these drugs while using the dosage of the dosage, increased the concentration and toxicity of these drugs. no time has been noted.
If necessary, the joint reception with Warfarin is recommended to carefully monitor the prothrombin time.
While taking macrolides with ergotamine and dihydroergotamine at the same time, their toxic action (vasospasm, dysesthesia) is possible.
Lincosamines reduce, and Tetracycline and chloramphenicol increase the effectiveness of azithromycin.
Pharmaceutically azithromycin is incompatible with Heparin.

Overdosage

Symptoms: nausea, vomiting, diarrhea, temporary hearing loss.
Treatment: symptomatic.

Keep out of reach of children at a temperature of 15 ° to 25 ° C.

2 years.
The shelf life of the prepared suspension is 5 days.