Amizon pills 250mg №20

Release form

Pills.

Composition

Amizon - coated tablets. 
1 pill contains amisone 0.125 g or 0.25 g.

Packaging

Pack of 10 and 20 pcs.

Mechanism of action

Amizon is a derivative of isonicotinic acid. Carries out an inhibitory effect on influenza viruses, has interferonogenic properties, increases the body's resistance to viral infections, provides anti-inflammatory, antipyretic and analgesic action.
The antiviral effect of Amizon is associated with its direct effect on the hemaglutinins of the influenza virus, as a result of which the virion loses its ability to adhere to target cells for further replication.
Anti-inflammatory effect is the result of stabilization of cell and lysosomal membranes, slowing down of basophil degranulation, antioxidant action, normalization of prostaglandins, cyclic nucleotides and energy metabolism in the inflammation. The antipyretic properties of this agent are due to the influence on the thermoregulatory centers of the brain. The analgesic effect of the drug is through the reticular formation of the brain stem.
Amizon enhances persistent immunity by increasing the level of endogenous Interferon in blood plasma by 3-4 times, lysozyme and increasing the titer of antibodies to infectious agents, as well as cellular - by stimulating the functional activity of T-lymphocytes and macrophages.This tool is a powerful inducer of endogenous interferon.

Amizon, indications for use

Treatment and prevention of diseases such as:

• influenza and respiratory viral infections;
• Infectious mononucleosis;
• measles, rubella, varicella, mumps infection;
• Fellinoz (cat scratch disease);
• non-specific chemoprophylaxis of hepatitis A, E.

In the complex therapy:

• viral, viral-bacterial and bacterial pneumonia and sore throats;
• cutaneous form of erysipeloid;
• meningitis and meningoencephalitis viral etiology;
• herpes infection;
• hepatitis A, E;
• pain syndromes in osteochondrosis, herniated intervertebral discs, arthritis, neuralgia.

Contraindications

Hypersensitivity to Iodine preparations and other components of the drug. The presence of allergic reactions, regardless of the nature of the allergen in the history. Severe organic lesions of the liver and kidneys. The first trimester of pregnancy, children under 6 years.

Dosage and administration

Amizon is taken orally after a meal, without chewing. The maximum single dose - 1 g, daily - 2 g. The recommended course of treatment, depending on the severity and etiology of the disease, is from 5 to 30 days.
Influenza and other respiratory viral infections: for therapeutic purposes, adults are prescribed 0.25 - 0.5 g 2-4 times a day for 5-7 days; children aged from 6 to 12 years appoint 0.125 g 2-3 times a day for 5-7 days.
When meningoencephalitis Amizon take 0.25 g 3 times a day for 10 days.
For the treatment of measles, rubella, chicken pox- children aged 6-7 years - 0.125 g 3 times a day; children aged 8-12 years - 0.125 g 4 times a day; children aged 13-14 years - 0.25 g 3 times a day; adolescents from 14 to 16 years old - 0.25 g 4 times a day; adults - 0.5 g 3 times a day.
For the treatment of mumps infection adults are prescribed 0.25 g 4 times a day with a moderate severity of the disease and 0.5 g 3 times a day with a severe course of the disease for 6-7 days; adolescents aged 12-14 years old are prescribed 0.25 g 3-4 times a day for 6-7 days.
For nonspecific chemoprophylaxis of parotid infection adults are prescribed 0.25 g 2 times a day for 10-14 days.
When infectious mononucleosis moderate - 0.25 g 3-4 times a day for adults and 0.125 g 3 times a day for children. With severe course - the first 2-3 days, 1.5-2 g per day for adults, up to 1 g per day for children. After achieving a clinical effect, the dose can be reduced by half.
For the treatment of Fellinoz adults are prescribed 0.25 g 3-4 times a day with a moderate severity of the disease and 0.5 g 3 times a day with a severe form of the disease.
Children aged 6-9 years - 0.125 g 3 times a day; 10-14 years - 0.125 g 4 times a day.
In the case of cutaneous articular erysipeloid adults - 0.5 g 3 times a day for 7-14 days.
For non-specific chemoprophylaxis of viral hepatitis A, E - 0.25 g 3 times a day, in complex therapy - 0.25 g 3 times a day during the first 5 days of illness.
In the complex therapy of pneumonia - 0.25 g 3 times a day for 10-15 days.
In the complex therapy of angina - 0.25 g 3-4 times a day for 5 days with a moderate severity of the disease; 0.5 g 3-4 times a day for 7 days with severe disease.
For pain syndromes, the drug is used 0.25–0.5 3-4 times a day.
For the prevention of influenza and ARVI Amizon is recommended to take in such doses:
for adults - 0.25 g per day for 3-5 days, then - at 0.25 g 1 time every 2-3 days for 2-3 weeks;
children 6-12 years old - 0.125 g every other day for 2-3 weeks;
adolescents from 12 to 16 years old - 0.25 g every other day for 2-3 weeks.

Use during pregnancy and lactation

The first trimester is contraindicated.

Side effects

Some patients may experience mild swelling of the oral mucosa and a feeling of bitterness in the mouth. Allergic reactions.

Special notes

Acceptance of the drug Amizon does not affect the ability to drive vehicles and various mechanical equipment. Data on use in women who are breastfeeding are not available.

Drug interaction

Amizon enhances the action of antibacterial, immunomodulatory agents. It is appropriate to combine this drug with Ascorbic acid and other Vitamins. Also Amizon can be assigned simultaneously with the use of recombinant interferon.