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Nigepan rectal candles №10
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Mechanism of action
The drug for the local treatment of hemorrhoids. Heparin is a direct acting anticoagulant. Activates antithrombin III, neutralizing a number of factors (XIIa, XIa, Xa, XIIIa). Disrupts the transfer of prothrombin to thrombin. When applied topically, heparin prevents the formation of blood clots, has anti-edema and anti-inflammatory effects, promotes the regeneration of connective tissue.
Benzocaine has a local anesthetic effect.
Cmax Plasma heparin is reached 30 minutes after rectal administration.
Indications and usage
- acute thrombosis of external and internal hemorrhoids.
Assign rectally to 1 suppository 2 times / day. The course of treatment is 10-14 days.
Adverse reactions
When applied according to indications in recommended doses, side effects are not established.
Contraindications
- hypersensitivity to the drug.
Pregnancy and breastfeeding
The safety of the drug Nigepan during pregnancy and lactation has not been established.
Special notes
It is established that when applied topically, the drug has no toxic, local irritating action.
Overdosage
Currently, no cases of drug overdose have been reported for Nigepan.
Drug Interactions
Drug interaction of the drug Nigepan is not described.
Storage conditions
The drug should be stored in a dry, cool, dark place.