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Bonifen pills coated 275mg №10
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Description
Film Coated Tablets
1 coated pill contains Naproxen sodium 275 mg
Packing
10 pieces.
Mechanism of action
NSAIDs. Bonifen has predominantly analgesic, as well as antipyretic and anti-inflammatory effects. The mechanism of action is associated with inhibition of the COX enzyme, which leads to inhibition of the synthesis of prostaglandins from arachidonic acid. Olgezin inhibits platelet aggregation.
Indications and usage
Rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, articular syndrome with exacerbation of gout; pain in the spine, neuralgia, myalgia, traumatic inflammation of the soft tissues and the musculoskeletal system. As an adjunct in infectious-inflammatory diseases of the upper respiratory tract, adnexitis, primary dysmenorrhea, headache and toothache.
Contraindications
Erosive and ulcerative lesions of the gastrointestinal tract in the acute phase, "aspirin triad", hematopoietic disorders, pronounced renal dysfunction (CC less than 20 ml / min), pronounced hepatic dysfunction, children under 1 year old; hypersensitivity to naproxen and other NSAIDs.
Pregnancy and Breastfeeding
Not recommended to appoint Bonifen Forte during pregnancy and lactation (breastfeeding).
Dosage and administration
Nalgezin pills are taken orally, after eating, drinking plenty of water. Children older than 16 years, and adults, including elderly patients, it is recommended to take the drug at 275 mg (1 tablet) after 8-12 hours, not exceeding the maximum daily dose of 825 mg (3 tablets).
Bonifen take for the time during which there is pain. With severe pain, you can use a loading dose (2 tablets).
Adverse reactions
On the part of the digestive system: heartburn, nausea, abdominal distension, erosive and ulcerative lesions, and Gastrointestinal bleeding.
From the side of the central nervous system: headache, dizziness, hearing loss.
Allergic reactions: skin rash, urticaria.
Other: possible violations of respiration or blood formation (thrombocytopenia, anemia), especially in individuals predisposed to these diseases; disorders of the liver and kidneys.
Storage conditions
In the dark place at a temperature of no higher than 25 ° C.