Diprospan ampoules 1ml №1

Composition: 1 ml solution for injection contains betamethasone disodium phosphate 2 mg and betamethasone dipropionate 5 mg; in 1 ml ampoules, in a box of 1 and 5 ampoules.

Mechanism of action

Anti-inflammatory, anti-allergic.
Slows down the release of interleukins 1 and 2, gamma-interferon from lymphocytes and macrophages, inflammatory mediators (eosinophils); induces the formation of lipocortins; reduces arachidonic acid metabolism.

Betamethasone disodium phosphate (easily soluble component) is rapidly absorbed and provides a rapid onset of effect. Betamethasone dipropionate, which has a slower absorption, provides a prolonged effect.

Indications and usage

Arthritis (rheumatoid, psoriatic), post-traumatic osteoarthritis, extra-articular rheumatism (synovitis, epicondylitis, tendosinovitis, myositis, fibrositis), lumbago, bronchial asthma, seasonal or perennial allergic rhinitis, psoriasis, nodular asthma, seasonal anesthesia, alopecia, afferent, and it is a non-artistystrophic, afferent, and aesthetic, temporal affection, seasonal or perennial allergic rhinitis, psoriasis, nodular asthma, seasonal or perennial allergic rhinitis, psoriasis, nodular asthma, seasonal or perennial allergic rhinitis, psoriasis, nesting, malignant neoplasms, collagenoses (disseminated lupus erythematosus, scleroderma, etc.).

V / m, deep in the gluteal region of 1–2 ml, with various dermatological diseases.
Intra-articular and periarticular - from 0.25 to 2 ml, depending on the size of the joint.
In / to (in the lesion), a single dose - up to 0.2 ml / cm2 (no more than 1 ml per week). Local infiltration: with bursitis - 0.25 to 1 ml (in acute form - up to 2 ml), with synovial cyst and tendosynovitis - from 0.25 to 0.5 ml, with tendinitis - 0.5 ml, with myositis, fibrositis - from 0.5 to 1 ml. If necessary, you can mix in a syringe with local anesthetics (1% procaine solution or 1% Lidocaine solution).

Adverse reactions

On the part of the gastrointestinal tract: digestive disorders, polyphagia, weight gain.
Metabolism: osteoporosis, growth retardation in children, deterioration in patients with diabetes mellitus, weighting of infections, corticoadrenal suppression.
Other: neurosis, edema.

Contraindications

Tuberculosis, osteoporosis, psychosis, peptic ulcer, fresh intestinal anastomoses and diverticula, glaucoma, diabetes, thrombophlebitis, renal failure, Cushing's syndrome, bacterial, fungal and viral infections, uveitis, nephritis, nephrotic syndrome, pregnancy, breast-feeding.

Pregnancy and breastfeeding

Not recommended.

You can not enter in / in. During treatment, vaccination and immunization are contraindicated.

Storage conditions

In the dark place at a temperature of 2-25 ° C, 5 years.