Buy Xamiol gel 15g
  • Buy Xamiol gel 15g

Xamiol gel 15g

$60.81
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Release form, composition and packaging

Gel for external use almost transparent, from colorless to almost white color; on the surface can be observed thin oily film.

betamethasone dipropionate

643 mcg

equivalent to betamethasone

500 mcg

calcipotriol monohydrate

52 mcg

equivalent to calcipotriol

50 mcg

Excipients: liquid paraffin 820 mg, polypropylene glycol 160 mg stearate, hydrogenated castor oil 20 mg.

Indications

- psoriasis of the scalp;

- psoriasis of mild and moderate severity of other parts of the body.

Dosing regimen

Outwardly.

Application of adults. Shake the vial before using it. The gel is applied with a thin layer to the affected areas of the scalp or to the psoriatic plaques of other parts of the body 1 time per day. The maximum daily dose of not more than 15 g; The maximum weekly dose should not exceed 100 g. The recommended duration of treatment is 4 weeks for psoriasis of the scalp and 8 weeks for skin lesions.
other parts of the body. The area of ​​application of the drug should not exceed 30% of the body surface. The drug should remain on the skin overnight or day to achieve the optimal therapeutic effect. Perhaps repeated use of the drug Xamiol under the supervision of a physician.

Adverse Effects

Side effects are classified depending on the frequency of occurrence: the most frequent> 1/10; frequent> 1/100 and <1/10; infrequent> 1/1000 and <1/100; rare> 1/10000 and <1/1000; very rare <1/10000.

Eye disorders:

Infrequent: eye irritation.

From the skin and skin appendages:

Frequent: itching.

Infrequent: rash, burning sensation, pain, irritation, dermatitis, exacerbation of psoriasis, folliculitis, dry skin, acne, pustular psoriasis.

Calcipotriol can cause local skin irritation, itching, burning and tingling, dry skin, erythema, rash, dermatitis, eczema, exacerbation of psoriasis, hyper and photosensitivity reactions, including very rare cases of angioedema and swelling of the face.

The development of skin atrophy, telangiectasia, stretch marks, folliculitis, hypertrichosis, perioral dermatitis, allergic contact dermatitis, depigmentation, colloid degeneration of the skin, as well as an increased risk of developing generalized pustular psoriasis are associated with prolonged external use of betamethasone (dipropionate).

Systemic reactions

Calcipotriol (very rare): hypercalcemia or hypercalciuria.

Associated with the use of betamethasone (rare, but sometimes heavy, especially with prolonged use, on large surfaces and with the use of occlusive dressings): suppression of the function of the adrenal cortex, cataracts, infections, increased intraocular pressure.

Systemic reactions occur more frequently when applying the drug under occlusive dressings and when applied to thin skin and skin folds, as well as during prolonged treatment when applied to large areas of skin.

Contraindications

- Diseases accompanied by impaired Calcium metabolism;

- Hypersensitivity to any of the components of the drug;

- severe renal and hepatic failure;

- viral (herpes, shingles), fungal, bacterial and parasitic infections of the skin, rosacea, acne rosacea, common acne, perioral dermatitis, skin
manifestations of tuberculosis and syphilis, skin atrophy, ulcers, wounds, itching in the perianal area and in the genital area, increased fragility of skin vessels, ichthyosis, striae;

- psoriatic erythroderma, drop-shaped, exfoliative, pustular psoriasis;

- age up to 18 years.

Pregnanacy and breastfeeding

In pregnancy, Xamiol is used only if the intended benefit to the mother outweighs the potential risk to the fetus.

If necessary, the use of the drug during lactation is recommended to refuse breastfeeding.

Application for violations of the liver

Contraindicated in severe liver failure.

Application for violations of kidney function

Contraindicated in severe renal failure.

Use in children

Is contraindicated to work up to 18 years.

Special notes

Do not use the drug on mucous membranes.

Use with caution when applied to the skin of the face and genitals. In case of accidental eye contact, unwanted adverse reactions are possible in the form of eye and skin irritation, conjunctivitis. In case of accidental contact with eyes, rinse with running water.

After applying the drug you need to wash your hands.

With the development of secondary infections, antimicrobial therapy should be prescribed.

Termination of psoriasis treatment with local corticosteroids with drugs may be associated with the risk of developing generalized pustular psoriasis and the effect of withdrawal. Therefore, after discontinuation of such treatment, it is necessary to continue clinical observation of the patient. During the period of treatment with Xamiol, it is recommended that the patient limit or avoid excessive exposure to natural or artificial sunlight. Calcipotriol (and preparations containing it) are allowed to be applied topically in combination with ultraviolet radiation only in cases where the attending physician considers the risk of undesirable side effects associated with such treatment justified.

The drug Xamiol contains butylhydroxytoluene (E321), which can cause local skin reactions (for example, contact dermatitis) or irritation of the eyes and mucous membranes.

To achieve an optimal therapeutic effect, it is not recommended to take a shower / bath or wash hair (in case of treatment of lesions of the scalp) immediately after applying the drug.

Influence on ability to drive motor transport and control mechanisms

Does not affect.

Overdosage

Symptoms: increased calcium in the blood, with the cessation of the drug is quickly restored; suppression of the function of the pituitary-adrenal system with the development of reversible secondary adrenal insufficiency.

Treatment: cancel the drug and conduct symptomatic therapy. In cases of chronic toxicity, GCS should be phased out.

Drug interactions

Not known

Pharmacy sales terms

Over the counter.

Storage conditions

At a temperature not higher than 25 ° С. Keep out of the reach of children.