Buy Epigen intimate aerosol 15ml
  • Buy Epigen intimate aerosol 15ml

Epigen intimate aerosol 15ml

$53.31
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Dosage form

Spray

Active ingredient

100 ml of the product contains: glycyrrhizic acid activated 0.1 g, which is equivalent to ammonium glycyrrhizinate.
Excipients: malic acid, fumaric acid, Ascorbic acid, folic acid, propylene glycol, tween-80, purified water.

Packaging

In a plastic bottle with a dispenser 15 ml funds. In packing 1 bottle with a spray nozzle for intravaginal use.

Mechanism of action

The active ingredient of Epigen Intim is activated glycyrrhizic acid, obtained by extraction from plant raw materials (licorice root). Activated glycyrrhizic acid has a complex action that includes antiviral, anti-inflammatory, immunostimulating, antipruritic and regenerating.
Activated glycyrrhizic acid induces the production of its own interferons. The immunostimulating effect is manifested by an increase in the number and activity of T-lymphocytes, a decrease in the concentration of immunoglobulin G and an increase in the concentration of immunoglobulins A and M. Activated glycyrrhizic acid has an antiviral effect on different types of DNA and RNA viruses in vitro and in vivo (Varicella Zoster, herpes simplex virus type I and II, cytomegalovirus, various types of human papillomavirus, including oncogenic).Activated glycyrrhizin interrupts viral replication in the early stages, causing the virion to exit the capsid, thereby preventing its penetration into the cells. Activated glycyrrhizic acid inactivates these viruses in non-toxic concentrations for normally functioning cells. Mutant virus strains resistant to Acyclovir and iodouridine are also highly sensitive to glycyrrhizic acid, as are non-mutant strains.
Anti-inflammatory activity of activated glycyrrhizic acid is combined with a stimulating effect on humoral and cellular immunity factors. Activated glycyrrhizic acid significantly inhibits the release of kinins and the synthesis of prostaglandins by connective tissue cells in the area of ​​inflammation. The regenerating effect is due to the improvement of the reparation of the skin and mucous membranes.

Indications and usage

- Treatment of human papillomavirus infection, incl. asymptomatic isolation of high-risk human papillomavirus in combined and complex therapy.
- Treatment of viral infections caused by the herpes simplex virus type I and II as part of complex therapy.
- Treatment of infection caused by the virus Varicella Zoster (shingles) as part of complex therapy.
- Treatment of cytomegalovirus infection as part of complex therapy.
- Prevention of recurrence of infections caused by the herpes simplex virus type I and II, Varicella Zoster virus, human papilloma virus, cytomegalovirus.
- Prevention and treatment of genital warts and cervical pathologies caused by human papillomavirus, cytomegalovirus.
- Prevention and treatment of conditions associated with a decrease in local immunity, incl. nonspecific vulvovaginitis, vulvovaginal candidiasis and bacterial vaginosis, as part of complex therapy.
- Discomfort in the genital area, accompanied by itching, burning and dry mucous membranes with a lack of ovarian function.

Contraindications

Hypersensitivity to the drug.

Pregnancy and Breastfeeding

The drug is approved for use during the entire period of pregnancy and lactation.

Dosage and administration

Externally, intravaginally and intraurethrally. Shake the can before use. At application to hold a cylinder in vertical position.
For external use the drug is applied to the affected surface from a distance of 4-5 cm by 1-2 strokes of the valve, which is the optimal therapeutic dose.
For intravaginal use a specially attached tip should be used. Remove the valve from the spray bottle and put on the nozzle valve. Then insert the nozzle into the vagina in the position of the patient lying on his back; the drug should be injected by 1-2 presses of the valve nozzle. After application, it is necessary to remain lying down for 5-10 minutes.
When used by menIn addition to external application, the drug is injected into the external opening of the urethra with 1-2 strokes of the spray valve.
For herpes virus type I shingles Epigenum sex is applied 6 times a day to the lesion for 5 days. With a persistent course of the disease, the treatment period is extended until the symptoms of the disease disappear.
In case of herpes virus infection type II (genital herpes), cytomegalovirus infection It is recommended to apply 5 times a day for 14 days outwardly and intravaginally, after relief of a relapse - outwardly and intravaginally 3 times a day for 10 days.
For the prevention of recurrence of genital herpes and cytomegalovirus infection apply externally and intravaginally from 18-20 days of the menstrual cycle until the end of menstruation, 2 times a day, morning and evening.
When human papillomavirus infection is recommended to use: before removal of condylo 3 times a day for the entire period of etiotropic therapy; against the background of destruction - 5 times a day for 10 days or more until healing; for the prevention of the next relapse - 3 times a day for 1 month.
For the prevention of progression of human papillomavirus infection It is recommended to use the drug before and after intercourse, as well as in the event of provoking factors: stress, fatigue, respiratory viral infections, microflora disorders, taking antibiotics, cytotoxic drugs - 3 times / day intravaginally and externally during the entire period of action of provoking factors.
In non-specific vulvovaginitis, bacterial vaginosis and vulvovaginal candidiasis the drug is recommended to be used intravaginally 3-4 times a day for 7-10 days. If necessary, repeat the treatment after 10 days. In the event of provoking factors (respiratory viral infections, antibiotics, cytotoxic drugs), the drug is prescribed 3 times a day intravaginally and externally during the entire period of exposure to the provoking factors.
With symptoms of discomfort in the genital area, accompanied by itching, burning sensation and dry mucous membranes (including with a lack of ovarian function and after intercourse), the drug is used 2 times a day (morning and evening) for 2-3 weeks. In order to prevent discomfort, apply regularly after intercourse.
As a prophylactic antiviral agent The drug is recommended to be used before and after intercourse.

Individual intolerance to the components of the drug.
Rarely: local allergic reactions, including in the form of contact dermatitis.

Special notes

The nozzle is washed with boiled water and soap and stored in the attached plastic bag. The design of the nozzle allows you to evenly irrigate the cervix and vaginal wall.
When used in inpatient conditions, intravaginal irrigation of preparations in mirrors can be carried out without a nozzle.
For effective action before using the drug does not require prior washing of the affected area.
If signs of intolerance appear, use of the drug should be discontinued.

Drug interactions

There were no interactions with the main groups of drugs used for the complex treatment of viral diseases (analgesics and antiseptics, anti-inflammatory and painkillers).
Synergism was found with simultaneous use of glycyrrhizic acid and other antiviral drugs, in particular, derivatives of acyclovir, iodouridine, Interferon and other immunomodulators.

Storage conditions

Store at room temperature (15 to 30 ° C).

Epigenes sex