Erinit pills 10mg №50

Dosage Form:

pills

Pharmachologic effect:

Venous vasodilator, has antianginal effect. Stimulates the formation of nitric oxide in the vascular wall, which is an endothelial relaxing factor. Reduces preload (expansion of peripheral veins and reduction of blood flow to the right atrium) and afterload (OPS) on the heart; reduces myocardial oxygen demand. Restores blood flow to the small endocardial vessels, improves in the epicardial coronary arteries, increases tolerance to physical activity in patients with coronary artery disease, angina. Reduces the pressure in the "small" circle of blood circulation. Compared with Nitroglycerin, it has a slower, but longer effect (up to 10 hours). When administered to the beginning of the effect - after 30-45 minutes (with sublingual - after 15-20 minutes), the duration is 4-5 hours.

Indications:

IHD, stenocardia (prophylaxis, including in the post-infarction period); CHF (as part of complex therapy).

Contraindications:

Hypersensitivity, hypotension, collapse, shock; acute myocardial infarction with arterial hypotension; intracranial hypertension, angle-closure glaucoma, impaired cerebral circulation (especially hemorrhagic stroke).

Side effects:

Allergic reactions, headache, dizziness, nausea, diarrhea, weakness, tachycardia, increased fatigue, anxiety, increased sweating, decreased blood pressure, orthostatic hypotension.

Dosage and administration:

Inside, 20 mg 3-4 times a day, if necessary, up to 40 mg 4 times a day, 80 mg 2 times a day can be prescribed. If necessary, sublingual application is possible. When used in combination with beta-blockers and BMCC, it is possible to administer it once a day (at a time when angina attacks occur more frequently).

Special instructions:

Due to the slow development of the effect, they are not used for the relief of strokes. During the period of treatment should be excluded the use of ethanol. With prolonged use may decrease therapeutic effect (due to the development of tolerance). When using the drug 1 time per day in combination with other antianginal drugs, the risk of tolerance is less.