Orsoten capsules 120mg №21

Indications and usage

Prolonged treatment of patients with conditions such as:
obesity (body mass index (BMI) ≥30 kg / m2);
overweight (BMI ≥28 kg / m2), incl. the presence of obesity-associated risk factors, combined with a moderately low-calorie diet.
Orsoten can be prescribed in combination with hypoglycemic drugs and / or a moderately low-calorie diet in patients with type 2 diabetes with overweight or obesity.

Contraindications

hypersensitivity to orlistat or any other components of Orsoten;
chronic malabsorption syndrome;
cholestasis;
pregnancy;
lactation;
children's age up to 18 years (efficiency and safety are not studied).

Adverse reactions

Adverse reactions to orlistat were mainly noted by the gastrointestinal tract and were due to an increased amount of fat in the feces. Commonly observed adverse reactions are mild and transient. The occurrence of these phenomena was observed at the initial stage of treatment during the first 3 months (but not more than one case). With prolonged use of orlistat, the number of adverse events decreases.
There are: flatulence, accompanied by discharge from the rectum, urge to stool, fatty / oily stools, oily discharge from the rectum, loose stools, soft stools, fat in the feces (steatorrhea), pain / discomfort in the abdomen, increased bowel movements, pain / discomfort in the rectum, imperative urge to stool, fecal incontinence, damage to the teeth and gums; hypoglycemia in patients with diabetes mellitus type 2, headache, anxiety, flu, fatigue, upper respiratory tract infections, urinary tract infections, dysmenorrhea, rarely allergic reactions (eg itching, rash, urticaria, angioedema, bronchospasm, anaphylaxis); very rarely - diverticulitis, cholelithiasis, hepatitis (possibly severe), bullous rash, increased levels of hepatic transaminases and alkaline thyroid.

Dosage and administration

Orsoten is taken orally with water, immediately before each main meal, during meals or no later than an hour after eating.
The recommended single dose of orlistat is 1 caps.120 mg each. If a meal is missed or food does not contain fat, then the intake of orlistat can be skipped.
Doses of orlistat over 120 mg 3 times a day do not enhance its therapeutic effect. The duration of therapy is no more than 2 years. Dose adjustment is not required for elderly patients or patients with impaired liver or kidney function.
The safety and efficacy of using orlistat in the treatment of children under the age of 18 years has not been established.

Storage conditions

Store in a cool and dark place, protected from light and moisture, at a temperature not higher than 25 ° C.