Salofalk pills 500mg N50

$52.50
Quantity

  • All payments are encrypted via SSL All payments are encrypted via SSL
  • Full Refund if you haven't received your order Full Refund if you haven't received your order

Salofalk has a local anti-inflammatory factor due to inhibition of cyclooxygenase and inhibits the migration, degranulation, neutrophil phagocytosis, as well as the secretion of lymphocyte immunoglobulins.

It has an antioxidant effect. Mesalazine can also trap radicals formed from reactive oxygen compounds. Results from in vitro studies provide an opportunity for the role of inhibition of lipoxygenases.

The effect on the content of PG in the intestinal mucosa was also shown. When taken orally, mesalazine has a predominantly local effect in the intestinal mucosa and submucosal layer, acting from the side of the intestinal lumen. Therefore, it is important that mesalazine is available in the area of ​​inflammation. The ratio of systemic bioavailability and plasma concentration of mesalazine is not significant in terms of therapeutic efficacy, but rather serves as a factor affecting safety.

Ensuring the release of the active substance in the right place helps that Salofalk granules are resistant to gastric juice and are pH-dependent (due to the coating in the form of Eudrajit l) and slow (due to the matrix structure of the granules) release of mesalazine.