Bifidumbacterin dry 5dos powder package №10

Active ingredient and dosage form

BIFIDUM BAKTERIN produced in several dosage forms: dry in vials and ampoules, bifidumbacterin powder in bags of laminated foil; Bifidumbacterin pills and in candles.
For the manufacture of the drug in vials and ampoules using the microbial mass of living bifidobacteria, lyophilized in a protective sugar-gelatin-dairy medium with a growing medium. Bifidumbacterin in powder - freeze-dried biomass of live bacteria, purified from the growing medium. One dose Bifidumbacterin in vials, ampoules, contains 10 ^ 7, in powder - 10 ^ 8 living cells.
Each of these packages contains 5 doses, in a pill and a candle - 1 dose.

is a dried microbial mass of live bifidobacteria immobilized on a sorbent (stone activated carbon). One dose Bifidumbacterin forte contains at least 10 ^ 7 colony forming units (CFU) of bifidobacteria (artificially created microcolonies). The drug is released in powder for 5 doses.

High therapeutic properties of bifidumbacterin forte are caused by colonization of the intestine with bifidobacteria, which in the immobilized state provide dense local colonization of the mucous membranes and, thus, restore normal flora and reparative process in the intestinal mucosa.

Mechanism of action

Bifidumbacterin - normalizes the intestinal microflora, immunomodulating agent. Bifidumbacterin is a probiotic and contains lyophilized live antagonist active bifidobacteria. It is an antagonist of a wide range of pathogenic and conditionally pathogenic microorganisms; activates the process of digestion and gastrointestinal function, metabolic processes, increases the nonspecific resistance of the organism.

Indications and usage

Bifidumbacterin is used to normalize the microbiocenosis of the gastrointestinal tract (correction of the intestinal microflora), increase the nonspecific resistance of the organism, stimulate the functional activity of the digestive system, for the prevention of intrahospital infections in maternity homes and hospitals,has detoxification properties.
Bifidumbacterin is prescribed to children and adults in the treatment of:
- intestinal dysbiosis (dysbiosis), incl. prophylaxis with antibiotic therapy, NSAIDs, hormones, radiation and Chemotherapy, stress;
- acute intestinal infections (shigellosis, salmonellosis, staphylococcal enterocolitis, rotavirus infection);
- intestinal infections of not established etiology and food toxicoinfections;
- intestinal dysbiosis accompanying the course of various diseases, including those with lesions of the digestive tract (gastric ulcer and duodenal ulcer, pancreatitis, cholecystitis, chronic diseases of the liver and biliary tract);
- chronic constipation;
- malabsorption syndromes;
- allergic diseases involving dysbacteriosis;
- dysbacteriosis in pneumonia, acute and chronic bronchitis, inflammatory diseases of the urogenital tract;
- bacterial vaginosis and colpitis;
- patients with a surgical profile during the period of preoperative preparation and after operations to correct the intestinal microbiocenosis with the pathology of the intestine, liver, pancreas;
For the prevention of dysbiosis in frequently ill SARS children and adults.
For the prevention of mastitis in nursing mothers at risk.
In children's practice: infectious (purulent-septic processes, pneumonia) and other diseases (complex therapy in young children; anemia, hypotrophy, rickets and allergic diathesis in weakened children; early transfer of infants to artificial feeding and feeding with donor milk).

Dosage and administration

Inside (tablets, powder):
Before use, the drug is mixed with the liquid part of the food, preferably fermented milk and give before meals. You can mix the drug with 30-50 ml of boiled water at room temperature and drink the resulting suspension without achieving complete dissolution of lactose. Infants are given during feeding, mixed with mother's milk.
For the prevention of dysbiosis bifidumbacterin is prescribed detyam up to 6 months 2.5 doses 1-2 times a day, children from 6 months to 3 years - 5 doses 1-2 times a day, children from 3 years and adults - 10 doses 1-2 times a day.
Preventive course 2-3 weeks 2-3 times a year.
For treatment bifidumbacterin is administered children up to 6 months 2.5 doses 2-6 times a day, children from 6 months to 7 years - 5 doses 3-5 times a day,children from 7 years and adults 10 doses 3-4 times a day.
The course of treatment from 5 to 15 days is determined by the nature and severity of the disease.
The course of treatment is 3-4 weeks. If necessary, the treatment can be repeated 2-3 times. Each course is held one month after the end of the previous course.
Patients with surgical pathology Bifidumbacterin is prescribed for 3-5 days before surgery and for 10-15 days after surgery for 5-10 doses 3 times a day.
Outwardly and locally:
For the prevention of mastitis: 20-30 minutes before feeding with a sterile swab moistened with the preparation solution (5 doses are dissolved in 10-15 ml of boiled water at room temperature), the nipples and areola of the mammary glands are treated for 5 days.
In gynecology: A tampon, abundantly moistened in a solution of the preparation (10 doses dissolved in 15-20 ml of boiled water at room temperature) is injected intravaginally for 2-3 hours or as candles. The course is 8-10 days. The therapeutic effect of bifidumbacterin in suppositories is also based on a high antagonistic activity against a wide range of pathogenic and conditionally pathogenic microbes. 

Contraindications

Not installed, except for individual intolerance to the drug. Bifidumbacterin should be administered with caution to children with lactase deficiency.

Adverse reactions

Not installed.

The drug should not be used in violation of the integrity of the individual packaging, violation of labeling. For dilution of the drug should not use water with a temperature above 40C and do not store bifidumbacterin in diluted form.

Drug Interactions

There are no undesirable effects when interacting with other drugs. The drug can be used in combination with antibacterial drugs.
The effect of enhancing Vitamins (especially group B), lower - antibiotics.

Storage conditions

The drug should be stored in a dry place at a temperature of 2 ° to 10 ° C.