Ceraxon solution 1000mg 4ml №5
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Solution for in / in and in / m introduction
Excipients: hydrochloric acid 1 M or sodium hydroxide 1 M (up to pH 6.7-7.1), water d / and - up to 4 ml.
Mechanism of action
Ceraxon is a nootropic drug.
Citicoline, being a precursor of key ultrastructural components of the cell membrane (mainly phospholipids), has a wide spectrum of action: it helps to restore damaged cell membranes, inhibits the action of phospholipases, preventing excessive formation of free radicals, and also prevents cell death by acting on the mechanisms of apoptosis.
In the acute period of a stroke, citicoline reduces the amount of damage to brain tissue, improves cholinergic transmission.
In traumatic brain injury, it reduces the duration of post-traumatic coma and the severity of neurological symptoms, besides citicoline reduces the duration of the recovery period.
In chronic hypoxia of the golvnogo brain citicoline is effective in the treatment of cognitive disorders, such as memory impairment, lack of initiative, difficulties encountered in performing daily activities and self-care. Increases the level of attention and consciousness, and also reduces the manifestation of amnesia.
Cerakson® effective in the treatment of sensory and motor neurological disorders of degenerative and vascular etiology.
Indications and usage
- acute period of ischemic stroke (as part of complex therapy);
- recovery period of ischemic and hemorrhagic strokes;
- traumatic brain injury, acute (as part of complex therapy) and the recovery period;
- cognitive and behavioral disorders in degenerative and vascular diseases of the brain.
- severe vagotonia (predominance of the parasympathetic part of the autonomic nervous system);
- children's and teenage age up to 18 years (due to the lack of sufficient clinical data);
- hypersensitivity to the drug.
Dosage and administration
In / in the drug is administered in the form of a slow injection (within 3-5 minutes, depending on the prescribed dose) or drip infusion (40-60 drops per minute). In / in the route of administration is preferable to the / m. When i / m injection should be repeated administration of the drug in the same place.
Acute ischemic stroke and traumatic brain injury: The recommended dose is 1000 mg every 12 hours from the first day after diagnosis; treatment duration is at least 6 weeks. 3-5 days after the start of treatment (if the function of swallowing is not impaired), a switch to the oral form of the drug is possible. Cerakson®.
The recovery period of ischemic and hemorrhagic strokes, the recovery period in traumatic brain injury, cognitive and behavioral disorders in degenerative and vascular diseases of the brain: The recommended dose is 500-2000 mg / day. (5-10 ml 1-2 times / day.). The dose and duration of treatment depend on the severity of the symptoms of the disease.
Side effects are very rare (<1/10 000), including isolated cases.
Allergic reactions: rash, pruritus, anaphylactic shock.
Nervous system: headache, dizziness, tremor, hallucinations, insomnia, agitation, numbness in paralyzed limbs, a stimulating effect on the parasympathetic system.
Gastrointestinal: nausea, vomiting, diarrhea, loss of appetite, changes in liver enzyme activity.
Other: feeling hot, short-term change in blood pressure, swelling, shortness of breath.
At a temperature not higher than 30 ° C.