Ferrum lek ampoules 100mg 2ml №5

Active ingredient

Ferrum Lekpills chewable brown, with white impregnations (marble), flat, with beveled edges.
1 pill contains iron (in the form of a complex of iron (III) hydroxide with polymaltose) - 100 mg;
Excipients: chocolate essence, aspartame (E951), talc, macrogol 6000, dextrates;
in a contour boxless package 10 pcs., in a cardboard bundle 3 packs.

Ferrum Lek oral syruptransparent, brown.
5 ml of syrup contain iron (in the form of a complex of iron (III) hydroxide with polymaltose) - 50 mg;
Excipients: sucrose, sorbitol, methyl parahydroxybenzoate, propyl parahydroxybenzoate, ethanol, creamy essence, purified water;
100 ml vials of dark glass, complete with a dosing spoon, in a cardboard box.

Ferrum Lek solution for i / m administration:
1 vial with a solution (2 ml) contains iron (in the form of a complex of iron (III) hydroxide with polyisomaltose) - 100 mg;
2 ml in ampoules, in a box of 5 or 50 ampoules.

Mechanism of action

Ferrum Lek - antianemic drug. In the preparation Ferrum Lek, iron is in the form of a complex compound of iron (III) hydroxide with polymaltose. This macromolecular complex is stable and does not release iron in the form of free ions. The complex is similar in structure to the natural compound of iron with ferritin, so that when Ferrum Lek is taken inside the drug, iron (III) from the intestine enters the blood through active absorption, which makes it almost impossible to overdose and poison the drug. Iron (III) hydroxide polymaltose complex does not possess prooxidant properties, which are inherent in iron (II) salts.
When using the drug, there is a gradual regression of clinical (weakness, fatigue, dizziness, tachycardia, dry skin) and laboratory symptoms of iron deficiency.
Ferrum Lek in the form of pills does not cause staining of the teeth.

After taking the drug inside the maximum absorption of iron occurs in the duodenum and jejunum. There is a correlation between the degree of iron deficiency and the amount of iron absorbed into the systemic circulation (the higher the iron deficiency, the better the absorption).
After the i / m injection, iron quickly enters the bloodstream: 15% of the dose - after 15 minutes, 44% - after 30 minutes. The maximum concentration of iron in the plasma is reached 24 hours after the injection. Biological T1 / 2 is 3-4 days.

Indications and usage

For oral administration:
- treatment of latent iron deficiency;
- treatment of iron deficiency anemia;
- prevention of iron deficiency during pregnancy and lactation.
For parenteral use (v / m): 
- for the treatment of iron deficiency conditions that require rapid and reliable replacement of iron loss in the body (severe post-hemorrhagic anemia);
- impaired iron absorption; the impossibility of complete absorption of iron from the gastrointestinal tract; malabsorption syndrome, ulcerative colitis and some other diseases of the gastrointestinal tract;
- intolerance to oral iron preparations;
- the ineffectiveness of the treatment of iron deficiency anemia with oral iron preparations.

Contraindications

- hemosiderosis, hemochromatosis;
- Violations of iron utilization mechanisms (for example, lead anemia, sideroachrestic anemia);
- anemia not associated with iron deficiency (for example, hemolytic anemia, thalassemia).

Dosage and administration

Chewable tablets
For the treatment of iron deficiency anemia appoint 1 tab. 2-3 times / day until normal hemoglobin level in the blood is reached (usually 2-3 months after the start of therapy). After that, iron supplementation should be continued for several months to restore the reserve of iron in the body (1 tab. 1 time per day).
During pregnancy It is recommended to take 1 tab. / day for the entire period.
For the treatment of latent iron deficiency and prevention of iron deficiency prescribed in a dose of 1 tab. / day.
Tablets are recommended to be taken during or immediately after a meal, chewing them or swallowing them whole.
Syrup
Ferrum Lek syrup is recommended to be taken during or immediately after a meal, can be mixed with fruit and vegetable juices or with nutritional mixtures (without reducing the activity of the drug). The daily dose may be taken in 1 or more doses.
With iron deficiency anemia in recommended doses, treatment is carried out within 2-3 months to achieve normal levels of hemoglobin in the blood.After that, taking the drug in prophylactic doses should be continued for several weeks to restore the reserve of iron in the body.
Daily doses of the drug for the prevention and treatment of iron deficiency, depending on the indications and the age of the patient are shown in the table.

* according to these indications, it is necessary to prescribe the drug in very low doses, so the use of syrup is not recommended.
1 dosing spoon contains 5 ml of syrup.

Solution for i / m administration
The drug for intramuscular injection is administered strictly intramuscularly and is not used intravenously (injection or infusion!).
The drug is injected through the day deep into the gluteus muscle alternately in the left or right.
Standard dosage: 
Children: 0.6 ml of the preparation / kg of body weight / day (3 mg of iron / kg / day).
Adult and older: 1-2 vials of the drug (100-200 mg of iron), depending on the level of hemoglobin.
Maximum Daily Dose: 
Children: 0.14 ml of the preparation / kg of body weight / day (7 mg of iron / kg / day).
Adults: 4.0 ml of the drug (200 mg of iron).
The ampoule is opened just before the introduction. Before use, carefully check the vial visually. Use only clear solution that does not contain sediment.
Intramuscular injection is injected slowly to avoid pain and staining of the skin in the upper outer square of the buttock with a needle 5-6 cm. Before injection, rub the skin, pull 2 ​​cm to the side so that after the needle is removed the injection channel is covered with skin to avoid leakage of fluid in the subcutaneous layers. During the insertion, the drawn skin is gradually released, and after the injection, press the injection site for 1 minute.

Adverse reactions

Gastrointestinal: rarely - a feeling of heaviness, discomfort in the stomach, nausea, constipation, diarrhea. When taking the drug, the feces are stained in a dark color, which is caused by the removal of non-absorbed iron and has no clinical significance.

Pregnancy and breastfeeding

In the course of controlled studies with the use of the drug in the II and III trimesters of pregnancy, there was no negative effect on the mother or fetus. No adverse effects on the fetus were detected when using the drug in the first trimester of pregnancy.

Special notes

In appointing Ferrum Lek to patients with diabetes mellitus, it should be borne in mind that 1 pill and 1 ml of syrup contains 0.04 XE.
The interaction of the drug with various food products: cereals (phytin), vegetables (oxalates), tea (tannins), as iron is part of the complex compound and does not enter into ionic interaction.
Taking the drug does not affect the results of fecal occult blood tests (selective for hemoglobin), so there is no need to stop taking the drug before conducting the study.
Use in pediatrics
Children are advised to prescribe the drug in the form of a syrup.

In cases of overdose for oral administration of Ferrum Lek, no signs of intoxication or signs of excessive iron intake have been described to date.

No interaction with other drugs has been noted.

The drug should be stored out of the reach of children at a temperature not higher than 25 ° C.

- 5 years.
Pharmacy sales terms
The drug is available on prescription.