Lincomycin capsules 250mg №20

Capsules

Composition

1 caps contains lincomycin hydrochloride 250 mg.

Packing

20 pcs.

Mechanism of action

Lincomycin has an antibacterial effect.

Indications and usage

Staphylococcal infections, sepsis, osteomyelitis.

Contraindications

Hypersensitivity, renal and hepatic failure, pregnancy.

Dosage and administration

When administered to adults - 500 mg 3-4 times / day. Children aged 1 month to 14 years inside - 30-60 mg / kg / day.

Adverse reactions

Gastrointestinal: nausea, vomiting, epigastric pain, diarrhea, glossitis, stomatitis; transient increase in liver transaminases and plasma bilirubin; with prolonged use in high doses, pseudomembranous colitis may develop.

Hemic and lymphatic: reversible leukopenia, neutropenia, thrombocytopenia.

Allergic reactions: urticaria, exfoliative dermatitis, angioedema, anaphylactic shock.

Effects due to chemotherapeutic action: candidiasis.

Drug Interactions

With simultaneous use with penicillins, cephalosporins, chloramphenicol or Erythromycin antagonism of antimicrobial action is possible.

With simultaneous use with aminoglycosides, synergism of action is possible.

With simultaneous use with agents for inhalation anesthesia or muscle relaxants of peripheral action, there is an increase in neuromuscular blockade, up to the development of apnea.

Taking antidiarrheal drugs reduces the effect of lincomycin.

Pharmaceutical Interaction

Pharmaceutically incompatible with ampicillin, barbiturates, theophylline, Calcium gluconate, Heparin and Magnesium sulfate.

Storage conditions

In a dry, dark place at a temperature of no higher than 15 ° C.