Ovestin candles vaginal 0,5mg №15

Dosage form

Vaginal suppositories

Composition

1 supp. contains estriol 0.5 mg.

Packing

15 pieces

Mechanism of action

Estriol is a natural estrogen. It contributes to the restoration of normal vaginal epithelium with its atrophic changes in pre- and postmenopause, contributes to the normalization of the microflora of the vagina, thereby increasing the resistance of the epithelium of the vagina to infectious and inflammatory processes. Since estriol has a short duration of action, taking the drug once daily in a dose does not cause endometrial proliferation and does not require additional progestogen therapy. Consequently, there is no withdrawal bleeding.
It has no significant effect on mineral and protein metabolism, blood glucose level, peripheral blood picture, plasma phosphorus content.

Indications and usage

Atrophy of the mucous membrane of the lower urogenital tract due to estrogen deficiency;
Pre- and postoperative treatment of postmenopausal women with vaginal access surgery;
Infertility caused by cervical factors;
For diagnostic purposes with unclear results of a vaginal smear on cytology.

Contraindications

Pregnancy; thrombosis, embolism; severe liver dysfunction; hormone-dependent tumors of the uterus or mammary glands; uterine bleeding of unknown etiology.

Dosage and administration

Vaginal suppositories are used at a dose of 500 mcg / day every day for the first 2-3 weeks; then gradually reduce the dose to 500 mcg / day, 2 times a week.

Adverse reactions

Sometimes (in violation of the dosing regimen): tension or pain in the mammary glands, nausea, pigment spots on the skin, hypersecretion of cervical mucus.

Seldom: headache, arterial hypertension, gastrocnemius muscle cramps, visual disturbances.

These side effects usually disappear during the first weeks of treatment.

Storage conditions

Store at room temperature (not exceeding 25 ° C).