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Sanpraz pills 40mg №10
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Active ingredient and dosage form
Sanpraz - enteric-coated tablets:
1 tab. pantoprazole sodium sesquihydrate 45.1 mg; 10, 20 or 30 pieces per pack.
Mechanism of action
H + -K + -ATP-ase inhibitor. Sanpraz blocks the final stage of secretion of hydrochloric (hydrochloric) acid, reduces the level of basal and stimulated (regardless of the type of stimulus) secretion of hydrochloric (hydrochloric) acid in the stomach. In duodenal ulcer associated with Helicobacter pylori, a decrease in gastric secretion increases the sensitivity of microorganism to antibiotics.
Indications and usage
- peptic ulcer of the stomach or duodenum in the acute phase;
- erosive gastritis (including associated with Helicobacter pylori);
- erosive and ulcerative lesions of the stomach and duodenum, associated with the intake of NSAIDs;
- Reflux esophagitis.
Contraindications
- dyspepsia neurotic genesis;
- Malignant diseases of the digestive tract;
- children's age (due to the lack of data on the use of Sanpraz in pediatric practice);
- Hypersensitivity to pantoprazole.
Adverse reactions
From the side of the central nervous system: headache; very rarely - depression, weakness, dizziness, blurred vision.
On the part of the digestive system: diarrhea, nausea, pain in the upper abdomen, constipation, flatulence; in isolated cases (1 case per 106 patients) - severe hepatocellular liver damage with jaundice, abnormal liver function.
Allergic reactions: skin rash, itching, skin flushing, Anaphylactic reactions (up to shock).
Other: painful tension of the mammary glands, hyperthermia.
Dosage and administration
Tablets Sanpraz take inside entirely (without crushing and dissolving), drinking plenty of fluids. Sanpraz is recommended to take 1 hour before breakfast, with a frequency of 2 times / day. second dose - 1 hour before dinner. The recommended dose of 40-80 mg / day.
Storage conditions
In the dark place at a temperature of 10 - 25 ° C. Shelf life - 2 years.