Tebantin capsules 300mg №100

Overdosage

Symptoms: dizziness, double vision, drowsiness, dysarthria, diarrhea.

Treatment: gastric lavage, taking activated charcoal, symptomatic therapy. Removal of Gabapentin from the body is possible through hemodialysis.

Inside, without chewing and washing down with the necessary amount of liquid, regardless of the meal.

Epilepsy. Adults and children over 12 years old: usually the effective dose is 900–1200 mg / day. The initial dose is 300 mg 3 times a day on the first day. The maximum dose is 3600 mg / day (in 3 equal doses). The maximum interval between doses when prescribing the drug 3 times a day should not exceed 12 hours. The desired therapeutic level of the drug in the blood can be achieved in a few days using the recommended regimens of the drug:

A. First day - 300 mg (1 capsule. 300 mg 1 time per day or 1 caps. 100 mg 3 times a day).
The second day - 600 mg (1 capsule. 300 mg 2 times a day or 2 capsules. 100 mg 3 times a day).
The third day - 900 mg (1 capsule. 300 mg 3 times a day or 3 capsules. 100 mg 3 times a day).
The fourth day is to increase the dose to 1200 mg in 3 doses, i.e. on 1 kaps. 400 mg 3 times a day.

B. On the first day, you can start by taking 1 caps. 300 mg 3 times, i.e. 900 mg / day. Then the daily dose may be increased to 1200 mg.

Depending on the effect obtained, the dose can be increased daily by 300-400 mg, while the maximum daily dose, divided into 3 doses, is 2400 mg, because There is currently not enough data on the efficacy and safety of higher doses.

Treatment of children aged 3–12 years: the recommended dose for children over 5 years old is 25–35 mg / kg / day, for children 3–4 years old - 40 mg / kg / day. The daily dose is divided into 3 doses. Recommended doses calculated for 1 kg of body weight are listed in Tables 2 and 3. The maximum daily dose in this age range is 35–40 mg / kg.

The course of treatment is carried out for a long time (2-3 years), then the dosage is gradually reduced.

Treatment of neuralgia in adults. Given the resulting effect and the tolerability of the drug, the doctor sets a therapeutic dose by titrating it. Depending on the individual patient's response, the maximum dose can reach 3600 mg / day.

Recommended regimens:

A. First day - 300 mg (1 capsule. 300 mg 1 time per day or 1 caps. 100 mg 3 times a day).
The second day - 600 mg (1 capsule. 300 mg 2 times a day or 2 capsules. 100 mg 3 times a day).
The third day - 900 mg (1 caps.300 mg 3 times a day or 3 caps. 100 mg 3 times a day).

B. With very intense pain on the first day, you can take 1 caps. 300 mg 3 times, i.e. 900 mg / day. Then within 1 week the daily dose can be increased to 1800 mg.
In some cases it may be necessary to further increase the dose. The maximum daily dose of 3600 mg is divided into 3 doses.

Weakened patients, with low body mass or undergone organ transplantation, the dose can be increased strictly by 100 mg per day.

Elderly patients in accordance with the age-related decrease in creatinine clearance, patients with renal insufficiency (Cl creatinine ≤80 ml / min), patients on hemodialysis, the dose should be selected individually.

Patients on hemodialysis who have not previously taken gabapentin are advised to prescribe a 300–400 mg saturating dose, then 200–300 mg every 4 hours of hemodialysis. In days free from dialysis, gabapentin cannot be taken.

The course of treatment varies from 1 week to 1 month, depending on the severity of the pain syndrome. The duration of treatment depends on the clinical response to therapy.

Precautionary measures

Use with caution during pregnancy and lactation, with renal failure.

In patients with diabetes mellitus, control of blood glucose level is necessary, sometimes it becomes necessary to change the dose of an antidiabetic drug.

At the first signs of acute pancreatitis (prolonged abdominal pain, nausea, repeated vomiting), gabapentin treatment should be stopped. The patient must be carefully examined (clinical and laboratory tests) in order to early diagnose acute pancreatitis.

In case of lactose intolerance, it should be noted that the capsule of 100 mg contains 22.14 mg of lactose, 300 mg - 66.43 mg, 400 mg - 88.56 mg.

If necessary, reduce the dose, cancel the drug or replace it with an alternative means should be gradually, for at least 1 week. Abrupt cessation of therapy may trigger status epilepticus.

The safety and efficacy of neuralgia therapy in patients aged less than 18 years have not been established. If adults develop drowsiness, ataxia, dizziness, fatigue, nausea and / or vomiting, weight gain, and in children with drowsiness, hyperkinesia and hostility, stop treatment and consult a doctor.

During the period of treatment, it is necessary to refrain from driving vehicles and practicing potentially hazardous activities that require increased concentration of attention and psychomotor speed.

When selecting the optimal therapeutic dose, it is not necessary to measure the plasma concentration of the drug. The drug is ineffective in generalized primary seizures, for example, in absences.

Storage conditions

At a temperature not higher than 30 ° C, 2 years.