Tykveol capsules 450mg №50

Active ingredient and dosage form

Tykveol capsules soft, gelatinous, oval shape with a longitudinal seam.
1 capsule contains pumpkin seed oil 450 mg;
polymer cans of 50 or 84 pcs., in a cardboard bundle of 1 can.

oil for oral administration - oily liquid from greenish-brown to red-brown color with a green shade in a thin layer, with a characteristic odor. The presence of sediment.
1 bottle contains pumpkin seed oil 100 ml;
in dark glass bottles of 100 ml., in a cardboard bundle one bottle.

oil extract - oily liquid from greenish-brown to red-brown color with a green shade in a thin layer, with a characteristic odor. The presence of sediment.
1 bottle contains pumpkin seed oil 20 ml;
in dropper bottles of 20 ml., in a cardboard bundle one bottle.

rectal suppositories from light green to dark green, cylindrical, with a pointed or rounded end.
1 suppository contains pumpkin seed oil 500 ml;
other ingredients: cocoa butter or polyethylene glycol, emulsifier;
in a blister strip package 5 pcs., in a carton pack of 1 or 2 packs.

Mechanism of action

- a complex preparation containing biologically active substances derived from pumpkin seeds.
The high content of tocopherols (alpha, beta, gamma, sigma isomers) and carotenoids has a pronounced antioxidant effect, which inhibits the processes of lipid peroxidation in biological membranes.
Essential phospholipids have a hepatoprotective effect, contribute to the restoration of the cell membrane of hepatocytes, its structure and function.
Essential fatty acids are involved in lipid metabolism, in the regulation of cholesterol and triglyceride metabolism, in the metabolism of arachidonic acid (as a biochemical precursor of prostaglandins).
The total set of pharmacological properties of biologically active substances in the drug Tykveol determines its anti-inflammatory and cytoprotective effect when applied topically.
Tykveol improves the functional state of the biliary tract, changing the chemical composition of bile, has a slight choleretic effect, reduces inflammation in the epithelium of the biliary system.
Tykveol, possessing antiandrogenic properties, reduces the proliferation of prostate gland cells, normalizes its function by improving microcirculation and anti-inflammatory action.

Indications and usage

For oral administration:
- cirrhosis of the liver;
- chronic hepatitis;
- fatty degeneration of the liver;
- Infectious hepatitis;
- toxic liver damage (drugs, industrial poisons, alcohol);
- cholecystitis (non-calculous);
- cholestasis;
- biliary dyskinesia;
- gastritis;
- colitis, enterocolitis (non-infectious genesis);
- hemorrhoids;
- atherosclerosis;
- prostatitis;
- benign prostatic hyperplasia.
For rectal use:
- chronic prostatitis;
- Benign prostatic hyperplasia stage I-II with concomitant prostatitis
For external and local use:
- herpes;
- dermatitis;
- psoriasis;
- eczema;
- burns and burn disease;
- cervical erosion;
- colpitis, endocervicitis;
- periodontal disease.

Dosage and administration

Tykveol oil for oral administration and Tykveol capsules are prescribed 30 minutes before meals 1 teaspoon 3-4 times / day for 1-3 months, or 4 capsules 3 times / day during or after meals.
With external and local use lubricate the affected areas 2-3 times / day.
With hemorrhoids and prostatitis (along with oral administration) prescribed microclysters 2 times / day.
At periodontal disease prescribe local drug applications.
In gynecological practice apply vaginal tampons soaked with a pumpkin dose of 10 ml.

Tykveol rectal suppositories injected into the rectum (pre-moistened with water) and 1 supp. 1-3 times / day
The course of treatment ranges from 10 days to 3 months, or conduct short courses of treatment for 10-15 days for 6 months.

Adverse reactions

Gastrointestinal: rarely - dyspepsia, diarrhea.
Other: allergic reactions.

Contraindications

Hypersensitivity to the drug.

Pregnancy and breastfeeding

Clinical data on the efficacy and safety of Tykveol in pregnancy and lactation are not available.

Special notes

In the case of side effects, it is necessary to reduce the dose of the drug.
Tykveol used as a monotherapy, and as part of complex therapy.
The drug is compatible with any food.
In inflammatory and degenerative processes of the mucous membrane of the upper gastrointestinal tract it is recommended to take Tykveol in the form of oil, you should avoid taking the drug in the form of capsules.
Use in pediatrics
Clinical data on the efficacy and safety of the drug in children are not available.

Overdosage

Symptoms: diarrhea.
Treatment: It is necessary to reduce the dose of the drug.

Drug Interactions

Tykveol not prescribed in combination with antacids, histamine H blockers₂-receptors, bismuth preparations, proton pump blockers.

Capsules and oil for ingestion should be stored in a dark place, out of the reach of children at a temperature from -10 ° to + 25 ° C.
Rectal suppositories should be stored in a dry, dark place, out of reach of children at a temperature not higher than 5 ° C.