Velaxin pills 37.5mg №28

)

Active ingredient and dosage form

Velaxin - oral tablets:

1 pill contains venlafaxine (as hydrochloride) 37.5 mg or 75 mg; 28 pieces per pack.

Mechanism of action

Velaxin has an antidepressant effect.

Indications and usage

Depression (with or without anxiety symptoms) in both outpatient and inpatient settings.

Prevention of relapse depression (with a positive therapeutic effect).

Contraindications

Hypersensitivity, simultaneous use of MAO inhibitors, severe renal dysfunction (glomerular filtration rate <10 ml / min) and / or liver (PF> 18 s), age up to 18 years (safety and efficacy for this age group are not proven), pregnancy or presumed pregnancy, lactation period (there are not enough data from controlled studies).

Adverse reactions

Common symptoms: weakness, fatigue.

On the part of the digestive tract: loss of appetite, constipation, nausea, vomiting, dry mouth, rarely - hepatitis.

On the part of metabolism: an increase in serum cholesterol level, a decrease in body weight, sometimes - a change in the results of laboratory tests of liver function, hyponatremia, syndrome of insufficient secretion of antidiuretic hormone.

Cardiovascular: arterial hypertension, hyperemia of the skin, postural hypotension, tachycardia.

From the side of the central nervous system: unusual dreams, dizziness, insomnia, irritability, paresthesia, stupor, increased muscle tone, tremor, yawning; sometimes apathy, hallucinations, muscle spasms, serotonin syndrome, rarely epileptic seizures, manic reactions, and symptoms resembling a neuroleptic malignant syndrome.

On the part of the urogenital system: disturbances of ejaculation, erection, anorgasmia, dysuric disorders (mainly - difficulty at the beginning of urination); sometimes - decreased libido, menorrhagia, urinary retention.

From the sense organs: accommodation disturbances, mydriasis, visual disturbances; infrequently - a violation of taste.

On the part of the skin: sweating; sometimes - photosensitivity reactions; rarely - erythema multiforme, Stevens-Johnson syndrome.

From the hemopoietic system: sometimes - hemorrhages into the skin (ecchymosis) and mucous membranes, thrombocytopenia; rarely, prolonged bleeding time.

Velaxin is taken orally, during meals.

The recommended starting dose is 75 mg in 2 doses (2 &№215; 37.5 mg) daily.

Special notes

Cancellation of the drug Velaksin: as with other antidepressants, abrupt cessation of therapy with venlafaxine, especially after high doses of the drug, can cause withdrawal symptoms, and therefore it is recommended to gradually reduce its dose before discontinuation of the drug. The duration of the period required to reduce the dose depends on the dose, the duration of therapy, as well as the individual sensitivity of the patient.

Storage conditions

To store a preparation in the dry, protected from light place at a temperature not higher than 25C. Shelf life 2 years.