Furacilin pills 20 mg №20

Composition

The composition of one tablet
Active ingredient: Nitrofural (furatsilin) ​​- 20 mg
Excipient: sodium chloride - 800 mg

Pharmacotherapeutic group:

Antimicrobial and antiprotozoal agent

Pharmacological properties

Pharmacodynamics

Antimicrobial agent, a derivative of nitrofuran. Bacterial flavoproteins, restoring the 5-nitro group, form highly reactive amino derivatives capable of causing conformational changes in proteins (including ribosomal) and other macromolecules, leading to the death of bacteria. Active against gram-positive and gram-negative bacteria (including Staphylococcus spp., Streptococcus spp., Escherichia coli, Clostridium perfringens). Resilience develops slowly and does not reach a high degree.
Pharmacokinetics
At external and local application absorption is insignificant. It penetrates histohematogenous barriers and is evenly distributed in fluids and tissues. The main path of metabolism - the restoration of the nitro group. Excreted by the kidneys and partly with bile.

Indications for use

External: purulent wounds, pressure sores, II-III degree burns, minor skin lesions (including abrasions, scratches, cracks, cuts).
Locally: blepharitis, conjunctivitis, osteomyelitis, empyema of the paranasal sinuses and pleura; urinary tract infections - washing of cavities, acute tonsillitis,stomatitis, gingivitis.
If necessary, please consult a physician before using the drug.

Dosage and administration

Locally, externally in the form of a 0.02% freshly prepared aqueous solution: immediately before use, one pill (20 mg of furatsilin), dissolved in 100 ml of distilled or warm boiled water. Hot water is recommended for faster dissolution. Then the solution is cooled to room temperature.
Outwardly: in the form of an aqueous 0.02% solution - irrigate wounds, apply wet dressings.
Locally: blepharitis, conjunctivitis - instillation of water 0.02% solution in the conjunctival sac. Osteomyelitis after surgery - washing the cavity, followed by the imposition of a wet dressing.

Contraindications

Hypersensitivity to nitrofural, nitrofuran derivatives and / or other components of the drug, bleeding, allergic dermatosis, pronounced renal dysfunction.

Side effect

Allergic reactions, dermatitis, skin itch are possible. If any of the side effects indicated in the instructions are aggravated, or any other side effects that are not indicated in the instructions are noted, you should immediately inform your doctor.

Carefully

The drug does not affect the ability to drive vehicles or engage in other potentially dangerous activities that require increased concentration and psychomotor speed.

Overdosage

No cases of overdose have been reported.

Interaction with other drugs

Not studied.