Flemoxin SoluTab pills 500mg №20

White to light yellow dispersible tablets, oval, with the company logo and “234” marking on one side and the risk dividing the pill in half on the other side

Composition

1 pill contains: Amoxicillin (in the form of trihydrate) 500 mg.
Excipients: dispersible cellulose, microcrystalline cellulose, crospovidone, vanillin, flavors (tangerine, lemon), saccharin, Magnesium stearate.

Packing

In the blister 4 tablets. In packing 5 blisters.

Mechanism of action

Flemoxin SoluTab - a broad-spectrum antibacterial agent. The active ingredient Flemoxin Solutab is amoxicillin trihydrate (semi-synthetic penicillin, beta-lactam antibacterial agent). It has a bactericidal action. Effective against Gram-negative and Gram-positive bacteria, such as: S. pneumoniae, Streptococcus pyogenes, Clostridium tetani, Neisseria gonorrhoeae, C. welchii, N. meningitidis, Moraxella catarralis, Staphylococcus aureus, Bacillus anthracis, asphidry, aspirant, asphitracry aureus, Bacillus anthracis, asphidry, asphiosis, auraus, aphus, etc. Helicobacter pylori. It is less effective against pathogens of intestinal infections: Escherichia coli, Shigella sonnei, Enterococcus faecalis, Salmonella typhi, Proteus mirabilis, Vibrio cholere. Inactive against microorganisms that produce beta-lactamase, as well as against indole-positive Proteus, Pseudomonas, Enterobacter.

Indications and usage

Infectious and inflammatory diseases caused by microorganisms sensitive to the drug:
- Infections of the respiratory system.
- Infections of the genitourinary system.
- Infections of the digestive tract.
- Infections of the skin and soft tissues.

Contraindications

Hypersensitivity to the drug or other beta-lactam antibiotics. The drug should be used with caution in case of polyvalent hypersensitivity to xenobiotics, infectious mononucleosis, lymphocytic leukemia, history of the gastrointestinal tract (especially for colitis associated with the use of antibiotics), renal failure, during pregnancy and lactation.

Pregnancy and Breastfeeding

The use of the drug Flemoxin Solutab during pregnancy and lactation is possible if the expected positive result from the use of the drug outweighs the risk of side effects. In small quantities, amoxicillin is excreted in breast milk, which can lead to the development of sensitization phenomena in a child.

Dosage and administration

The drug is taken orally. The drug is prescribed regardless of the meal. The pill can be swallowed whole, divided into parts or chewed, washed down with a glass of water, and can also be diluted in water to form a syrup (in 20 ml) or a suspension (in 100 ml), which have a pleasant fruity taste. Dosing regimen set individually, taking into account the severity of the disease, the sensitivity of the pathogen to the drug, the patient's age. In the case of infectious and inflammatory diseases of mild and moderate severity, the use of the drug is recommended according to the following scheme: adults and children over 10 years old are prescribed 500-750 mg 2 times / day or 375-500 mg 3 times / day; children aged 3 to 10 years, appoint 375 mg 2 times / day or 250 mg 3 times / day; children aged 1 to 3 years should be prescribed 250 mg 2 times / day or 125 mg 3 times / day.
The daily dose of the drug for children (including children up to 1 year) is 30-60 mg / kg / day, divided into 2-3 doses.
For difficult-to-reach foci of infection (for example, acute otitis media), a triple dose is recommended.
In chronic diseases, recurrent infections, and severe infections, adults are prescribed 0.75–1 g 3 times / day; children - 60 mg / kg / day, divided into 3 doses.
In acute uncomplicated gonorrhea, 3 g of the drug is prescribed in 1 administration in combination with 1 g of probenecid.
Patients with impaired renal function with CK≤10 ml / min reduce the dose of the drug by 15-50%.
In case of mild to moderate infections, the drug is taken for 5-7 days. However, for infections caused by Streptococcus pyogenes, the duration of treatment should be at least 10 days.
In the treatment of chronic diseases, infections of the severe course of the duration of the drug should be determined by the clinical picture of the disease.
The drug should be continued for 48 hours after the disappearance of the symptoms of the disease.

It is necessary to administer the drug to patients with infectious mononucleosis and lymphocytic leukemia with caution, since there is a high probability of the appearance of exanthema of non-allergic genesis. The presence of erythroderma in history is not a contraindication for the appointment of Flemoxin Solutab. Cross-resistance and cross-hypersensitivity with penicillin preparations, cephalosporins are possible. As with the use of other penicillin preparations, the development of superinfection is possible. The occurrence of severe diarrhea, characteristic of pseudomembranous colitis, is an indication for the abolition of drugs.

Drug Interactions

Probenecid, phenylbutazone, oxyphenbutazone, and to a lesser extent, Acetylsalicylic acid and sulfinpyrazone inhibit the tubular secretion of penicillin preparations, which leads to an increase in T1 / 2 and an increase in plasma amoxicillin concentration.
Bactericidal antibiotics (including aminoglycosides, cephalosporins, Vancomycin, rifampicin) while receiving concurrently show synergism.
Antagonism is possible when taken with certain bacteriostatic drugs (for example, chloramphenicol, sulfonamides).
Simultaneous administration of amoxicillin with estrogen-containing oral contraceptives may decrease the effectiveness of the latter and increase the risk of acyclic bleeding.
The simultaneous use of amoxicillin with Allopurinol does not increase the frequency of skin reactions in contrast to the combination of allopurinol with ampicillin.

Overdosage

An overdose of Flemoxin Solutab may have the following symptoms: vomiting, nausea, diarrhea. Due to vomiting and diarrhea, dehydration of the body and disruption of water and electrolyte balance can occur. In case of overdose, enterosorbents, laxatives of the salt group, hydration measures are prescribed.

Storage conditions

The drug should be stored out of the reach of children, dry, protected from light, at a temperature not exceeding 25 ° C.